Neural stem cell therapies and hypoxic-ischemic brain injury

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Stem Cell Therapy in Hypoxic Ischemic Encephalopathy

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Neuroprotective Therapies after Perinatal Hypoxic-Ischemic Brain Injury

Hypoxic-ischemic (HI) brain injury is one of the main causes of disabilities in term-born infants. It is the result of a deprivation of oxygen and glucose in the neural tissue. As one of the most important causes of brain damage in the newborn period, the neonatal HI event is a devastating condition that can lead to long-term neurological deficits or even death. The pattern of this injury occur...

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stem cell therapy in hypoxic ischemic encephalopathy

introduction there are one million deaths from asphyxia in newborn annually. management of this newborn is only supportive. autologuse stem cell therapy may reduce mortality and long term morbidity. outcome of asphyxiated newborn is related to damage cns cells. stem cells prevent apoptosis and induce repairmen of injured neurons. methods in a review study all article related to three keywords o...

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Neural stem cell (NSC) proliferation and differentiation are required to replace neurons damaged or lost after hypoxic-ischemic events and recover brain function. Periostin (POSTN), a novel matricellular protein, plays pivotal roles in the survival, migration, and regeneration of various cell types, but its function in NSCs of neonatal rodent brain is still unknown. The purpose of this study wa...

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ژورنال

عنوان ژورنال: Progress in Neurobiology

سال: 2019

ISSN: 0301-0082

DOI: 10.1016/j.pneurobio.2018.05.004